| Alpine | 68 | Long Beach | 66 | Solana Beach | 15 | ||
| Anaheim | 59 | Los Angeles | 83 | Temecula | 29 | ||
| Arcadia (via 395) | 114 | Mammoth Lakes | 358 | Tijuana, Mexico | 45 | ||
| Arrowhead | 103 | Monterey | 426 | Tucson, AZ | 447 | ||
| Bakersfield | 193 | Mount Laguna | 88 | Twenty-Nine Palms | 146 | ||
| Banning (via 15/79/74/79) | 93 | National City | 43 | Valley Center | 31 | ||
| Barstow | 150 | Needles | 283 | Ventura | 162 | ||
| Beaumont (via 15/79/74/79) | 86 | Newport Beach | 50 | Victorville | 113 | ||
| Big Bear Lake | 110 | Oakland | 486 | Vista | 9 | ||
| Bishop | 318 | Ocean Beach | 40 | Warner Hot Springs | 72 | ||
| Blythe | 229 | Olivenhain | 16 | Whittier | 80 | ||
| Bonsall | 13 | Ontario | 60 | Yosemite (via 5/41) | 992 | ||
| Borrego Springs | 92 | Pacific Beach | 36 | Yosemite (via 5/14) | 426 | ||
| Brawley | 166 | Pala | 24 | Yuma, AZ | 218 | ||
| Capistrano Beach | 26 | Palm Springs | 106 | ||||
| Cardiff | 13 | Palomar Mountain | 50 | ||||
| Carlsbad | 3 | Pasadena | 97 | ||||
| Chula Vista | 47 | Perris | 52 | ||||
| Corona Del Mar | 42 | Phoenix, AZ | 392 | ||||
| Coronado | 40 | Pomona | 92 | ||||
| Costa Mesa | 40 | Poway | 41 | ||||
| Dana Point | 29 | Ramona | 37 | ||||
| Death Valley (via 15/127) | 209 | Rancho Bernardo | 28 | ||||
| Del Mar | 17 | Rancho Penasquitos | 34 | ||||
| Desert Hot Springs | 115 | Rancho Santa Fe | 17 | ||||
| Disneyland | 59 | Redondo Beach | 79 | ||||
| El Cajon | 48 | Reno, NV (via 395) | 550 | ||||
| El Centro | 154 | Reno, NV | 602 | ||||
| Elsinor | 46 | Ridgecrest | 237 | ||||
| Encinitas | 12 | Riverside | 66 | ||||
| Fallbrook | 20 | Sacramento (via 5/101/680/80) | 579 | ||||
| Fresno | 299 | Sacramento (via 5/99) | 473 | ||||
| Hemet | 62 | Sacramento (via 5) | 465 | ||||
| Henshaw | 49 | Salinas | 408 | ||||
| Huntington Beach | 60 | Salton Sea | 151 | ||||
| Idyllwild | 85 | San Bernardino | 78 | ||||
| Indio | 126 | San Clemente | 22 | ||||
| Inglewood | 85 | San Diego | 37 | ||||
| Julian | 60 | San Elijo | 18 | ||||
| La Costa | 12 | San Francisco (via 5) | 460 | ||||
| Laguna Beach | 35 | San Francisco (via 101) | 517 | ||||
| La Jolla | 27 | San Jacinto | 64 | ||||
| Lake Havasu | 297 | San Jose (via 101) | 465 | ||||
| Lakeside | 54 | San Luis Obispo | 294 | ||||
| Lake Tahoe (via 395) | 512 | San Simeon (Hearst Castle) | 305 | ||||
| Lake Tahoe (via 5/50) | 577 | San Marcos | 13 | ||||
| La Mesa | 45 | Santa Ana | 51 | ||||
| Lancaster | 151 | Santa Barbara | 171 | ||||
| Las Vegas | 304 | Santa Monica | 95 | ||||
| Lemon Grove | 49 | San Ysidro | 52 | ||||
| Leucadia | 11 | Santa's Villiage | 102 |