Chem 211 - Exam #4 Sample
Sample Exams are designed to give you an idea of the types of questions you can expect. Problems for this exam will likely be similar to the sample problems, and the questions from a previous exam shown below. However, remember that you are responsible for all material that we have discussed in lecture, as well as material from Chem210, as it relates to the current content.
| Chapter | Problem Numbers |
| 23 | 1,2,3,4,7,11,17,22,37 |
| 24 | 1,4,5,10,11,15,16,17,36,37,38a,k |
| 25 | 1,2,3,9 |
Sample questions from previous exams:
1. On a bottle of liquid detergent I saw the following organic compounds. Please give structures for each. Then, show how you would synthesize one of them using organic reagents, and any other chemicals you need.
2. Show structures for each of the following:
3. (a) Show how to produce an hemiacetal starting with an alcohol and an aldehyde. (b) Then, show how you could convert this hemiacetal into an acetal. (c) Show how you would produce an intramolecular hemiacetal starting with D-glucose, and the cyclic product..
4. Starting with benzene, show how to produce in succession (a) nitrobenzene, (b) aniline, (c) benzenediazonium chloride, and (d) chlorobenzene.
5. Show the products for (a) acid and (b) base hydrolysis of N-methylacetamide.
6. (a) Show how to produce ethylamine starting with ammonia and ethyl bromide. (b) Then explain why you would also produce triethylamine.
7. Draw structrues for each of the following (for amino acids, show only the side chain):
8. For the amino acid alanine, show the complete structure, including charges, that would exist at each of the following pH's.
pH 1
pH 7
pH 11
9. Starting with the amino acids Glu, Cys, and Gly, show the complete structure for the tripeptide containing these amino acids in the order shown. Then, explain why this naturally occurring peptide, which is named glutathione, can be involved in oxidation-reduction reactions.
10. Please draw the structure of dATP. Show at least 4 different types of functional groups or types of bonds that are present in this molecule.
11. Give an accurate description, or an example, to describe the primary, secondary, tertiary and quarternary structures for a protein.
12. Chymotrypsin, like all serine proteases, uses a charge-relay-network consisting of Asp, His, and Ser. Describe how this arrangement of amino acids allows for catalysis to proceed. Show the reaction mechanism for cleavage of an amide (peptide) bond by this enzyme.
13. Define each of the following: